Science White Papers Falling Flat? Here’s a Formula for Better Performance.

It’s about understanding your audience, offering real value, and distributing where your buyers are.

illustration of C&EN white paper landing page

White papers are a powerful tool science marketers can use to drive inbound leads. Great white papers tell your audience how brands solve problems and — most importantly — why it matters to them. White papers are an investment of time and research, but they can drive high-quality leads well past their publication dates with the right strategy. But not all white papers are created equal. We examined high-performing white paper examples (those that over-performed lead goals by at least 3x) to understand what made them so successful.

High-Performing Science White Paper Examples (and What They Have in Common)

For every white paper that becomes a high-performing asset, countless others underperform expectations and even fail to make back the money invested in their creation. Sometimes this is because the white paper itself is not aligned with audience needs — but it can also be because the distribution plan was lacking, leaving high-quality work out to dry. 

Here’s what we learned from examining successful white papers and what they all have in common.

1. Know and appeal to audiences that matter

Cresset white paper example

The key to creating a high-performing white paper is first to define your audience, as well as their pain points and challenges. A white paper that drives leads includes not only why the solution matters to the industry but how it solves a specific problem for the reader. Building a white paper that appeals to your readers requires listening to your audience and building trust with that group—goals that need audience research to accomplish. This research will ensure that your framing speaks directly to what matters to your reader.

In this white paper example from Cresset, C&EN BrandLab took a forward-thinking idea—using AI in drug discovery—and grounded the vision in audience research, relying on expert voices and trends of the moment to give the idea context. C&EN BrandLab spoke to stakeholders—both internal at Cresset as well as industry experts—to define the audience that matters for this white paper, and to gain knowledge of their pain points, challenges, and interests. Though a consumer research study was not used in the planning of this white paper, approaching audience research through 1:1 discussions proved fruitful (and can be an excellent tactic if resources are limited or when a consumer research study might not be possible).

Based on these discussions, the team at C&EN BrandLab realized that they needed to take a two-pronged approach to discussing the topic at hand: 

  • First, the white paper needed to explain the stakes for solving this problem in terms of worldwide impact—faster development of drugs is a net good, and using AI in drug discovery can aid in this process. 
  • Next, the focus was narrowed to discuss what was specifically at stake for the intended audience—AI has the potential to speed up time-consuming, but informative, calculations for early stage drug discovery.

With this editorial approach defined, the team was able to more clearly discuss the topic and proposed solutions. The white paper explains the current state of computer-aided drug design (CADD), the impact that accelerated speed driven by machine learning-enabled CADD could have on pharmaceutical development, and the concrete steps needed to operationalize the solution. In addition, research highlighted within the white paper shows that the entire field is working in this direction, indicating that this solution is on the way. This framing clarifies not only how the solution builds off of existing technology, but importantly, how machine learning-enabled CADD could address current pain points for key stakeholders.

2. Provide actionable takeaways 

Reading an excellent white paper feels more like learning something new than being marketed to. You get to give your audience a new perspective on your industry or the problem you’re solving, highlighting the magnitude of your solution’s impact on the field—and providing something of value for the audience to hopefully put into use. 

This white paper example from TA Instruments highlights the importance of including valuable takeaways readers can immediately apply to their business. The white paper first provides research emphasizing the urgency of solving the plastic waste problem. From there, it outlines concrete steps scientists can take to shift how they view the utility of recycled mixed plastic. This includes:

  • Introducing technology (e.g. instruments for standard materials analysis) that scientists can use to obtain information that helps them counteract and manage variation in recycled plastic
  • Providing proof points for why utilizing recycled plastic is challenging and how managing variation is a solution to some of the challenges  

The efforts resulted in a high-performing asset that could be used as a resource for many in the scientific industry working on this problem— introducing the science of a real-world challenge and offering a readily available solution to enact.

3. Have a clear and targeted distribution strategy

While defining an audience and creating something of value to them are important, there is little truth to the idea that “if you build it, they will come.” White papers need strategic distribution plans that find and engage their target audiences and clearly emphasize the asset’s value to that audience. Importantly, these distribution plans should think well beyond the initial launch moment to get the most ROI from a white paper. Beyond where they plan to distribute the asset itself, marketers should think about how to deconstruct and repurpose specific elements of the white paper—graphics, key research findings, infographics or other snippets that could serve as social media cutdowns, for example—and promote across channels to continue to drive readers back to the white paper.

Scheduling distribution in an editorial calendar is a good first step to ensure promotion doesn’t fall by the wayside. White papers can get even more traction when promoted alongside a relevant event or story. For example, an infographic on plastic types and their risks could be tied to the news of recycling legislation or discoveries like this story on plastics in our bodies.

If you’re looking for a partner to help create white papers that generate leads, talk to the experts at C&EN BrandLab. We’ll show you how white papers can help drive brand and solution awareness. Contact us for a consultation to meet your lead generation goals.

Start generating more leads today!

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Sammi Wang

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Sammi is the General Manager China of eChinaChem, where she has worked since 2005 and previously served as Vice President and Sales Manager. eChinaChem offers news media, conferences and events, as well as education and training services in the chemical, pharmaceutical, and healthcare sectors in China. Before eChinaChem, she worked at GlobalSources as an Account Executive. Sammi received her MBA from the University of International Business and Economics and her undergraduate degree from Yantai University.

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Uwe Riemeyer is a seasoned Global Media Specialist with over 25 years of experience in media sales, consulting, and planning, primarily for the global chemical industry. Since 1997, he has been affiliated with ACS and operates his own successful media business in Germany. Uwe’s expertise spans all B2B industry segments and related media outlets, supported by a solid foundation in economics and an initial career in the automotive industry. His comprehensive knowledge and strategic insights make him a key player in media planning and consulting.

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Jim Beckwith brings his skills to ACS after a lengthy media consulting career in both for-profit and non-profit media. He specializes in helping advertising partners “connect the dots” between their marketing/lead generation objectives and the wide range of opportunities in the ACS Media portfolio. Jim works with advertisers based in the Southeast and Eastern U.S.

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Except for a brief hiatus in 2022, Pete Manfre has been a fixture at ACS since 2015, helping clients navigate the complex B2B digital landscape. Over the years, Pete has gained the trust of many science marketing leaders with his honest and straightforward approach. His unique insights and expertise have benefitted the small companies looking to gain traction with new potential customers and the well-known industry brands looking to elevate their thought leadership and capture bigger market-share.

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Jordan is a Senior Editor at C&EN BrandLab. While earning her Ph.D. in chemistry she also pursued her passion for writing and communication, including a stint as a science reporter during the COVID-19 pandemic. She now funnels her love of words and chemistry into creating compelling science stories and content.

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Jesse Harris is a Senior Editor at C&EN BrandLab. He has been creating internet content since 2016, and has Master’s degrees in both chemistry and chemical engineering. He loves helping STEM experts communicate their science more impactfully.

Shane M Hanlon Ph.D.

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Shane leads BrandLab’s strategic initiatives and projects. As a conservation biologist turned science communicator and storyteller, Shane brings years of creative and relationship-building experience to BrandLab from his work in the federal government, the National Academies, and scientific membership nonprofits. He is an adjunct professor at the University of Pittsburgh, from which he obtained his B.S. in Ecology and Evolution, and holds a Ph.D. in biology from the University of Memphis.

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Heather co-leads account management at C&EN BrandLab. She utilizes efficiency and strategy when working with our clients and production teams within C&EN to deliver effective and engaging campaigns. Heather has a passion for telling dynamic stories through multimedia communication channels and brings creativity, curiosity, and charisma to BrandLab partnerships. She obtained her B.S. in International Relations from The College of Wooster in Ohio. 

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Cynthia Graham-Tappan is an accomplished sales leader with over 15+ years’ experience leading global B2B sales teams within the publishing & media industries.  She has held executive positions with The New York Times, Dow Jones, Agence France Presse, Hearst Corporation and currently oversee Sales & Strategic Partnerships for ACS.   Cynthia has a proven expertise in crafting strategic partnerships, steering high-performing sales teams, and propelling revenue growth. Cynthia also has extensive experience in performance management, market research, digital media monetization, and business development.

Cynthia received her B.S. degree from Towson University and recently completed Executive Education courses with The Yale School of Management and London Business School.  Cynthia resides in Maryland with her husband, and she is a proud mom of four kids.

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Kenneth is a creative leader with 20 years of experience in in-house and boutique design agencies. He is currently senior creative director for the American Chemical Society’s marketing and communications team. Previously, he was senior creative director for ACS Publications, an international scientific publisher that serves chemistry and related sciences. Kenneth is passionate about translating client business goals into impactful and innovative advertising solutions. Under his leadership, ACS has won numerous awards and accolades for its exceptional design work.